
← Pharm to Table19 Aug 2025 · 36 min
SE4:E4 - MedChem Masters: Molecules, Mentors and Mindsets
<p>In this episode, Dani and LC interview Dr. Shane Krska, recipient of the ACS Arthur C. Cope Award, and Dr. Petr Vachal, recipient of the ACS Earle B. Barnes Award for Leadership in Chemical Research Management. Shane shares his pioneering work in catalytic methods and high-throughput experimentation (HTE) for drug discovery, while Petr discusses his leadership role driving innovation at Merck. They reflect on their career journeys from graduate school to industry, emphasizing personal growth and the importance on taking on diverse roles. We wrap it up by asking Shane and Petr what has made them the most proud over their 20+ year careers - which spans from innovations in direct-to-biology for accelerating design-make-test to advancing peptides as a modality of the future!</p><p><br /></p><p><strong>Read the papers we discussed today:</strong></p><p><a href="https://pubs.acs.org/doi/pdf/10.1021/acscatal.2c05159" target="_blank" rel="ugc noopener noreferrer">The Catalysis Laboratory at Merck: 20 Years of CatalyzingInnovation</a></p><p><a href="https://pubs.rsc.org/en/content/articlelanding/2016/cs/c5cs00628g" target="_blank" rel="ugc noopener noreferrer">The medicinal chemist's toolbox for late stage functionalization of drug-like molecules</a></p><p><a href="https://pubs.acs.org/doi/10.1021/ja902462q" target="_blank" rel="ugc noopener noreferrer">Highly Efficient Asymmetric Synthesis of Sitagliptin</a></p><p>Follow the Pharm to Table podcast on X - @PharmtoTablePod</p><p>Visit our website at <a href="https://podcasters.spotify.com/pod/show/pharm-to-table" target="_blank" rel="ugc noopener noreferrer">https://podcasters.spotify.com/pod/show/pharm-to-table</a> </p><p><br /></p>