
← Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health24 aug · 15 min
54. Stress, Cortisol & Histamine: The Hidden Loop
54. Stress, Cortisol & Histamine: The Hidden Loop
In this episode of The Histamine Well, Joanne explores the powerful connection between stress, cortisol, mast cell activation, and histamine intolerance. She explains how chronic stress can keep the nervous system trapped in fight-or-flight mode, trigger histamine release, and contribute to symptoms such as itching, flushing, headaches, sinus congestion, digestive issues, and skin reactions. You’ll learn how the HPA axis responds to stress, why cortisol is helpful in the short term, and what ...