CRISPR changes the world and unlocks GMO 2.0

What is CRISPR-Cas9 and how is it going to revolutionize the world of GMO crops?

References

de Lange, O., Binder, A. and Lahaye, T. (2014), From dead leaf, to new life: TAL effectors as tools for synthetic biology. Plant J

→ Review article on TAL effectors by yours truly

Ishino Y, Shinagawa H, Makino K, Amemura M, Nakata A. Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product. J Bacteriol. 1987

→ Paper first describing CRISPR in 1987

Interview with the 2020 Nobel Prize laureate in chemistry, Emmanuelle Charpentier, recorded in Stockholm on 12 December 2022.

Martin Jinek et al.,A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity.Science337,816-821(2012).

—> First paper describing use of CRISPR as a programmable DNA endonuclease

Updates on Global Regulatory Landscape for Gene-Edited Crops

By Clement Dionglay, January 24, 2024

https://www.isaaa.org/blog/entry/default.asp?BlogDate=1/24/2024