The Climate Biotech Podcast

← The Climate Biotech Podcast10 dec 2025 · 1 u 00 min

Reimagining Bioreactors to Solve Manufacturing Bottlenecks with Brian Heligman

Reimagining Bioreactors to Solve Manufacturing Bottlenecks with Brian Heligman10 dec 20251 u 00 min

Biomanufacturing doesn’t fail for lack of clever biology; it stalls at the factory gate. We sit down with Biosphere CEO Brian Heligman to unpack how a materials scientist’s journey through batteries and perovskites led to a bold thesis for the bioeconomy: change the constraints of the bioreactor and you change everything downstream. Instead of miles of steam lines and fragile commissioning, Biosphere is betting on UV-sterilized stainless systems, modern automation, and a full-stack approach t...