
← The Dr. Brighten Show11 aug · 32 min
Endometriosis Inflammation: Why This Disease May Affect More Than Your Pelvis
Endometriosis inflammation may have implications far beyond pelvic pain, including associations with cardiovascular disease, autoimmune conditions, and long-term health risks. In this episode of The Dr. Brighten Show, Dr. Jolene Brighten explains what the research actually shows, why a normal CRP doesn’t necessarily rule out inflammation, and what women and clinicians should understand about endometriosis as a whole-body disease. View the complete show notes at Dr. Brighten: https://drbrighten.com/podcasts/endometriosis-inflammation/
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What You'll Learn in This Episode
Why endometriosis is about much more than misplaced tissue or retrograde menstruation
How immune dysregulation and inflammatory cytokines may contribute to the endometriosis environment
Why normal CRP or hs-CRP doesn't necessarily mean inflammation isn't present
The important difference between localized, regional, and systemic inflammation
How inflammatory signaling, nerve growth, and blood vessel formation may help explain severe pain
Why progesterone resistance is an important but often overlooked part of endometriosis biology
How lesions may produce estrogen locally and contribute to a self-sustaining inflammatory environment
What research suggests about endometriosis and long-term cardiovascular risk
How chronic inflammation, oxidative stress, endothelial dysfunction, and altered hormone signaling could potentially connect endometriosis and cardiovascular health