New Science of Weight Loss | A Masterclass

GLP-1 medications are transforming obesity treatment, but they're only one piece of the puzzle. In this masterclass, I bring together insights from Dr Terry Simpson, Dr Federica Amati, Dr Mauricio Gonzalez, Dr Christos Mantzoros, and Dr Stephan Guyenet to explain how these medications work, why "food noise" matters, and what it really takes to improve long-term metabolic health.

What We Cover

How GLP-1 medications regulate appetite and food noise

Why obesity is more complex than willpower

Semaglutide vs tirzepatide and newer medications

Nutrition and resistance training while taking GLP-1s

The role of fibre, protein, and Mediterranean-style eating

Common misconceptions and side effects

I hope this episode helps you better understand both the promise and the limitations of GLP-1 medications, while highlighting the importance of lifestyle alongside any medical treatment.

Why Terry Simpson Started Taking a GLP-1 (00:00)

What Is Food Noise, Really? (04:59)

Why GLP-1 Drugs Work So Well (10:16)