Ep. 177 Part I: Menopause, Estrogen & the Alzheimer's Brain

Welcome to Thriving in Midlife: The Women's Guide to Wellness, Longevity & Hormones After 40, your trusted space for women over 40 who want better health, more energy, balanced hormones, and practical wellness strategies that actually work.

I’m your host, Kellie Lupsha, a high-performance health coach, and I’m excited to guide you on a journey toward greater vitality, energy, and well-being.

Did you know that changes associated with Alzheimer’s disease can begin in the brain 20 to 30 years before symptoms appear?

In this episode, Kellie explores the powerful connection between menopause, estrogen, brain health, cognitive function, and Alzheimer’s risk in women.

Menopause is often viewed primarily as a reproductive transition, but estrogen plays important roles in the brain. As estrogen levels fluctuate and decline during perimenopause and menopause, women may experience changes such as brain fog, anxiety, insomnia, memory concerns, and difficulty finding words.

Kellie breaks down why these symptoms deserve attention and why supporting your brain and metabolic health during midlife can be an important part of healthy aging.

What You’ll Learn

*Why menopause can impact brain health

Understand why declining estrogen is connected to changes in brain structure, energy production, cognition, and neurological function.

*Four ways estrogen supports the brain

Learn how estrogen supports mitochondrial function, helps regulate amyloid pathways, supports antioxidant defenses, and helps maintain white matter integrity.

*The connection between estrogen and oxidative stress