76. Injectable Buprenorphine in Pregnancy

A new randomized controlled trial of injectable buprenorphine in pregnancy.

Winhusen TJ, Lofwall MR, Kropp F, et al. Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum: A Randomized Clinical Trial. JAMA Intern Med. Published online March 16, 2026.

We also discuss the kindling effect  in opioid withdrawal, and how insurance changes can destabilize patients in recovery.

Psychopharmacology: Repeated fentanyl abstinence intensifies opioid withdrawal and induces a proinflammatory state in striatal microglia

STAT: How the insurance system quietly undoes recovery from addiction

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES.

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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Original theme music: composed and performed by Benjamin Kennedy

Audio editing: Michael Bonanno

Executive producer: Dr. Patrick Beeman