Episode 510 - Harold & Kumar Go to White Castle (2004)

Carrying the stoner-comedy torch first blazed by Cheech & Chong, two college buddies (Kal Penn & John Cho) have a night for the ages as they attempt to cure their munchy cravings of White Castle burgers.  Co-starring Neil Patrick Harris, along with numerous guest appearances from Christopher Meloni, Ryan Reynolds, Anthony Anderson, Fred Willard, Malin Akerman and Jamie Kennedy.