Your Aging Brain Gets Help From Your Blood. A New Hope for Alzheimer’s? | Dr. Julia Belk, PhD #85

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Could our understanding of the brain’s immune system be completely rewritten? In this episode of Alzheimer's Breakthrough, host Dr. Josh Helman, MD speaks with Dr. Julia Belk, PhD from Stanford University about her ground-breaking research published in Nature.

Dr. Belk and her team discovered that in adult humans, microglia the resident immune cells responsible for maintaining brain health are not permanently isolated in the brain throughout life as previously believed. Instead, they are actively replaced by circulating immune cells originating from the blood and bone marrow. This paradigm-shifting discovery opens extraordinary new possibilities for treating Alzheimer’s disease, leveraging engineered cell therapies, and crossing the blood-brain barrier!

In this episode:

00:00 Introduction: Can Blood Help the Aging Brain?