Dr. Paika Podcast

← Dr. Paika Podcast1. Okt. · 22 Min.

How Long Tirzepatide Stays in Your Body (Half-Life Explained) | Mounjaro/Zepbound Guide

How Long Tirzepatide Stays in Your Body (Half-Life Explained) | Mounjaro/Zepbound Guide1. Okt.22 Min.

#Tirzepatide #Mounjaro #Zepbound #GLP1 #WeightLoss

How long does tirzepatide (Mounjaro, Zepbound) actually stay in your system? It's not 5 days. In this video, I explain tirzepatide's half-life using 4 clocks it sets in your body. Those clocks explain when side effects hit and what to do if you miss a dose. They also explain why a 1-week pause before surgery may not be enough, why the birth control rule is 4 weeks, and how long the drug takes to clear after your last shot.

Then we get to the clock that matters most: what happens after you stop. You'll see what the SURMOUNT-4 trial found about weight regain and why muscle loss is the real risk. I'll also share how I regained 45 pounds when my own structure disappeared, and the 2 paths that protect your results.

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TIMESTAMPS

00:00 Why "it's gone in 5 days" is wrong

01:26 What tirzepatide is and how it works