#40 - Anaphylaxis: Don't Bee Alarmed!

<p><strong>First Principles of Anaphylaxis</strong></p><p>Anaphylaxis is one of those conditions you never want to miss, but it can be stressful knowing exactly what to do when every second counts. In this episode, we break it all down from first principles.</p><p>We'll cover how to recognise anaphylaxis early, what's actually happening in the body, why adrenaline is the treatment of choice, and the key steps in management. As always, this isn't about memorising guidelines, it's about understanding the <em>why</em> behind your decisions, so you'll feel more confident in OSCEs, on the wards, and in clinical practice.</p><p>So grab your matcha, your laptop, or your favourite study snack (just maybe double check it isn't hiding any peanuts 🥜), and let's dive into anaphylaxis. From airway and breathing checks to adrenaline and beyond, because knowing what to do in those first few moments can make all the difference.</p><p><br /></p><p>=== Other Links ===</p><p>Notion notes: https://app.notion.com/p/1pm/40-Anaphylaxis-3b9ef1d0b55f801dbfb1f285f3de9da9?source=copy_link </p><p><br /></p><p>================</p><p>Recording date: 27/5/2026</p><p>Guests: Angela Goh, Julia Jolly, and Jasmyne Le</p><p>Producer: Jasmyne Le</p><p><br /></p><p>If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠</p><p>© First Principles of Medicine 2026</p>