I’ve Studied Aging For 30 Years… Intermittent Fasting Won’t Make You Live Longer

<p>Dr. Matt Kaeberlein is a biologist of aging, the CEO of Optispan, and a co-founder of the Dog Aging Project. He is also the founding director of the University of Washington’s Healthy Aging and Longevity Research Institute and has published over 250 papers on longevity. In this conversation, he breaks down why direct-to-consumer longevity products deserve skepticism, what the data actually says about rapamycin and intermittent fasting, and which biomarkers and scans are worth your money.</p><p>In this episode, we discuss:<br>(1:58) Why Matt Kaeberlein Resigned From a Longevity Academy in 2024<br>(9:14) How to Spot Longevity Hype and Misleading Supplement Claims<br>(16:31) Lifespan vs. Healthspan: Have We Really Slowed Aging?<br>(22:01) Curing Cancer Adds 2.5 Years. Slowing Aging Could Add 20.<br>(24:43) Should Aging Be Classified as a Disease?<br>(30:59) The Hallmarks of Aging Explained<br>(39:39) Is VO2 Max the Best Longevity Metric?<br>(47:29) The Intermittent Fasting Myth: What Mouse Studies Show<br>(51:38) What Is Rapamycin and Does It Slow Aging?<br>(58:00) Inside the Dog Aging Project’s Rapamycin Trial<br>(1:01:19) Does Matt Kaeberlein Recommend Rapamycin?<br>(1:04:37) Protein Maxing and mTOR: Does More Protein Speed Aging?<br>(1:11:54) Are Biological Age Tests Accurate?<br>(1:19:49) The One Biological Age Clock He Trusts: LinAge2<br>(1:24:29) Best Longevity Spend: $100 vs. $1,000 a Month</p><p><br></p><p>Learn more about Dr. Matt Kaeberlein here:<br>Website: <a href="https://kaeberleinlab.org">https://kaeberleinlab.org</a><br>Optispan: <a href="https://www.optispan.life">https://www.optispan.life</a><br>Dog Aging Project: <a href="https://dogagingproject.org">https://dogagingproject.org</a><br>Instagram: <a href="https://www.instagram.com/mkaeberlein">https://www.instagram.com/mkaeberlein</a><br>X: <a href="https://x.com/mkaeberlein">https://x.com/mkaeberlein</a><br>LinkedIn: <a href="https://www.linkedin.com/in/mkaeberlein">https://www.linkedin.com/in/mkaeberlein</a></p><p><br></p><p>Watch this episode on Youtube: https://youtu.be/IrfBCWadCm0</p><p><br></p><p>📸 Connect with us on IG: <a href="https://instagram.com/growthminds.podcast">https://instagram.com/growthminds.podcast</a></p><p>Made possible by: Jumpspeak: ⁠<a href="https://www.jumpspeak.com%E2%81%A0">https://www.jumpspeak.com⁠</a></p><p>Follow Sean Kim<br>Instagram: <a href="https://www.instagram.com/heyseankim/?hl=en">https://www.instagram.com/heyseankim/?hl=en</a><br>X: <a href="http