Gynecologic Oncology Update

← Gynecologic Oncology Update29. Sept. · 48 Min.

Glucocorticoid Receptor Antagonists for Ovarian Cancer — An Interview with Professor Nicoletta Colombo

Glucocorticoid Receptor Antagonists for Ovarian Cancer — An Interview with Professor Nicoletta Colombo29. Sept.48 Min.

Featuring an interview with Professor Nicoletta Colombo, including the following topics:

Mechanistic effects and rationale underlying the use of relacorilant/nab paclitaxel (0:00)Rationale underlying the study design of the Phase II BELLA trial and avenues for future exploration (8:31)Definition of platinum ineligibility; importance of platinum-containing chemotherapy for patients with ovarian cancer (14:02)Findings from a Phase II trial and the subsequent confirmatory Phase III ROSELLA study (20:25)Phase III ROSELLA study: Subgroup analyses, patient-reported outcomes, insights into overall survival data and common adverse events (29:43)Considerations for therapeutic selection and sequencing of novel therapies; ongoing and future investigations (38:46)

CME information and select publications