CRISPR, MPRA, and the genetics of mental health

In this episode, Jess McAfee, PhD, and Alejandro Gomez discuss how massively parallel reporter assays, CRISPRi, single-cell RNA sequencing, and other molecular biology tools can help researchers better understand genetic variants linked to psychiatric disorders. They also share their winding early-career paths, what drew them to CRISPR, and why persistence, mentorship, and curiosity matter in science.