Therapeutic Estrogen for Prostate Cancer: Hot Flashes & Better Sleep | Dr. Richard Wasserbug

What if one of the hardest parts of androgen deprivation therapy is not simply low testosterone—but the loss of estradiol that comes with it?

Dr. Richard Wassersug brings a rare dual perspective to that question.

He is a PhD evolutionary biologist, former professor of anatomy and neurobiology, prostate cancer quality-of-life researcher, co-developer of an androgen deprivation education program, and a patient who has used transdermal estradiol for more than two decades. His experience helped drive a deeper investigation into whether estrogen delivered through the skin could suppress testosterone while avoiding some of the burdens associated with standard LHRH-based ADT.

In this episode, you’ll learn:

🟠 Why men need estradiol for **brain, bone, sexual, and overall health.**

🟠 What the **PATCH research** suggests about transdermal estradiol, cancer control, and quality of life.

🟠 Why **hot flashes, poor sleep, fatigue, and cognitive symptoms** may reflect more than testosterone loss.

🟠 What men should know about **gynecomastia, monitoring, exercise, and shared decision-making** before considering this emerging strategy.

decision-making before considering this emerging strategy.

Chapters

00:00 ADT Side Effects Question

00:54 Podcast Disclaimers