Isabella Cooper – Part 2 – Ketogenic Diet and Cancer: What the Science Actually Shows

<p>In this episode of The Feldman Protocol, how does insulin influence cancer cell behavior — and what does that mean for metabolic approaches to the disease? Dave sits down with Isabella Cooper (PhD) to explore the glucose-ketone index and its practical limits, the role of glutamine alongside glucose in cancer metabolism, how mitochondrial dysfunction and cardiolipin loss may relate to tumor progression, the case for high-dose intravenous vitamin C, osteocyte biology and the surprising systemic roles of osteocalcin, and what makes a rigorous research culture.</p><p><br></p><p>🔥 This episode is sponsored by us --</p><p>Own Your Labs 👉 `https://ownyourlabs.com/sp/49`</p><p> Private blood testing services</p><p>🩸Over 300 blood tests</p><p>💰Extremely affordable</p><p>❤️ We love our customers</p><p>(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)</p><p><br></p><p>🔗 CONNECT WITH DAVE FELDMAN:</p><p>Main Channel: `https://youtube.com/@realDaveFeldman`</p><p>X/Twitter: `https://x.com/realDaveFeldman`</p><p>Instagram: `https://instagram.com/realDaveFeldman`</p><p>Website: `https://thefeldmanprotocol.com`</p><p><br></p><p>⏱ Chapters</p><p><br></p><p>0:00 – Cold open &amp; intro</p><p>1:08 – Cancer metabolism overview</p><p>2:24 – Glucose-ketone index explained</p><p>5:01 – Lean mass hypersponders &amp; glucose</p><p>9:18 – Acetone measurement &amp; respiration</p><p>13:49 – Insulin, ketones &amp; cancer signaling</p><p>19:05 – Growth factors &amp; VEGF discussion</p><p>25:29 – Stomach acidity &amp; nutrient absorption</p><p>32:08 – How cancer cells originate</p><p>35:43 – Cardiolipin, melatonin &amp; apoptosis</p><p>43:05 – Diet quality &amp; food as function</p><p>52:14 – Chemotherapy &amp; metabolic protocols</p><p>1:03:36 – Patient outcomes &amp; biopsy risks</p><p>1:14:32 – IV vitamin C trial findings</p><p>1:22:07 – Ideal cancer metabolism trial design</p><p>1:29:36 – Sunlight, melanin &amp; mitochondria</p><p>1:37:20 – Osteocyte biology &amp; osteocalcin</p><p>1:46:43 – Research culture &amp; scientific rigor</p><p>1:54:36 – Most underappreciated biomarker</p><p><br></p><p>#FeldmanProtocol #DaveFeldman #IsabellaCooper #CancerMetabolism #KetogenicDiet #Mitochondria #Insulin #GlucoseKetoneIndex #Osteocalcin #IntravenousVitaminC #Ketosis #MetabolicHealth #LowCarbScience #CancerResearch #Cardiolipin #Osteocytes #BloodWork #Hyperinsulinemia #MitochondrialHealth #PodcastScience</p><p><br></p>