The Optispan Podcast with Matt Kaeberlein

← The Optispan Podcast with Matt Kaeberlein3. Apr. · 42 Min.

Longevity Doctors Rank the Most Hyped Supplements (AMA with Dr. Kaeberlein and Dr. Byrne)

Longevity Doctors Rank the Most Hyped Supplements (AMA with Dr. Kaeberlein and Dr. Byrne)3. Apr.42 Min.

<p>Dr. Matt Kaeberlein and Clinical Director Dr. Nicki Byrne tackle your most pressing supplement questions in this AMA episode, cutting through the hype to give you science-backed answers you can actually use. From CoQ10 and statins to sulforaphane influencer hype, creatine and kidney disease, and why a popular longevity doctor may be losing Matt&#39;s trust, this episode covers a lot of ground. If you&#39;ve ever wondered which supplements are worth your money and which ones belong in the trash, this one&#39;s for you.<strong>Timestamps:</strong>00:00 — Cold open highlights01:18 — Episode intro: AMA focused on supplements01:57 — CoQ10: Does it help with statin-induced muscle pain?04:43 — Is there any reason to take CoQ10 on its own?05:23 — Taurine: Promising or overhyped?07:35 — Astaxanthin: What the evidence actually shows09:45 — Why supplement research is structurally flawed11:05 — Creatine for plant-based dieters12:22 — Creatine and kidney disease: What the data says15:48 — Matt, Nicki &amp; Nick&#39;s current creatine doses17:00 — Vitamin D: Reference ranges vs. optimal ranges18:57 — Vitamin K2: Bone density, vascular calcification &amp; dosing caution21:55 — Sulforaphane: Great biology, limited evidence, too much hype27:21 — Resveratrol, hormesis &amp; plant defense chemicals27:58 — Fish oil &amp; the omega index: Why Matt supplements even though he eats fish29:23 — Mark Hyman, sirtuins &amp; the problem with longevity influencers32:08 — Lithium &amp; SGLT2 inhibitors: Matt adjusts his dose live34:15 — Is lithium orotate safe? Addressing the liver carcinogen concern36:26 — Is there an OTC alternative to rapamycin?37:40 — Berberine vs. metformin: More similar than you think38:58 — What do Matt, Nicki &amp; Nick actually take?41:48 — Wrap-up &amp; teaser: Deep dive on magnesium coming soon</p>