The Space Show Presents Dr. Tiffany Hennessa Of The NRL and the ISS National Lab On Microbial Research

The Space Show Presents Dr. Tiffany Hennessa, Friday, 8-14-26.

Meeting Summary

This Space Show live broadcast interviewed Dr. Tiffany Hennessa, a research biologist at the Naval Research Lab (NRL) who studies microbial research for space applications. Dr. Hennessy discussed her work using microbes and fungi like Aspergillus in space experiments, including missions to the ISS and Artemis I to the moon, where she studies how microgravity affects microbial growth, nutrient uptake, and the production of specialized compounds. We talked about technical challenges of conducting experiments in space, including hardware limitations, sample size restrictions, and the need for simplicity in design to accommodate astronauts’ time constraints. Dr. Hennessa explained that space biology research is highly competitive and difficult to fund, with costs being a significant factor in project planning. The discussion also touched on potential applications for defense and biomanufacturing, as well as future opportunities with commercial space stations and robotic laboratories.

Detailed Summary

Tiffany discussed her journey from plant science PhD at the University of Maryland to her current work at NRL on space biology research. She explained how she was initially tasked with working on the Artemis I program, ISS experiments, and Antarctic balloon experiments. When asked about the types of microbes used in space research, Tiffany clarified that “microbes” was a blanket term for microorganisms like yeast, fungi, and bacteria, and explained that the choice of organism depends on the research question and factors like feasibility, safety, and hardware compatibility with space environments.

Tiffany explained a space mission where her team sent Aspergillus niger spores to the moon on Artemis I, packed in gelatin capsules with phase-changing media to allow germination during the two-week journey. The experiment was designed to be passive, with the fungi growing in microgravity while experiencing gamma radiation, though no cameras were included to capture the process in real time. David asked about the medical implications of Aspergillus niger, to which Tiffany confirmed it can cause health issues for immunocompromised individuals, though it is generally tolerable for healthy people.

Tiffany discussed the potential for finding fungi on other planets, noting their 50% genomic homology with humans and their resilience to extreme conditions, including high temperatures and radiation. Sh