Distillations | Science History Institute

← Distillations | Science History Institute11 sep 2025 · 54 min

The CRISPR Babies

The CRISPR Babies11 sep 202554 min

In 2018 news broke that a Chinese scientist, He Jiankui, had used CRISPR to edit human embryos, and twin girls had been born as a result. The story set off an explosive bioethical controversy. As gene editing expert Kiran Musunuru put it, "He Jiankui's genetic misadventures were the biggest medical story of the century so far." Both scientists and the public had a lot of questions. What was the unmet medical need that justified the gene editing? Was the science ready for prime time? And, if it was, was He Jiankui the right scientist to do it? Seven years later these questions are far from resolved.

Credits Host: Alexis Pedrick

Executive Producer: Mariel Carr

Producer: Rigoberto Hernandez

Associate Producer: Sarah Kaplan

Audio Engineer: Samia Bouzid

Music by Blue Dot Sessions

Resource List Baylis, Françoise. Altered Inheritance: CRISPR and the Ethics of Human Genome Editing. Cambridge, MA: Harvard University Press, 2019.

CBS News. "Chinese Researcher Claims He Helped Make First Gene-Edited Babies." CBS News, November 26, 2018.

CBS News. "Chinese Scientist Behind Gene-Edited Babies Sentenced to 3 Years in Prison." CBS News, December 30, 2019.

Cobb, Matthew. As Gods: A Moral History of the Genetic Age. New York: Basic Books, 2022.

Greely, Henry T. CRISPR People: The Science and Ethics of Editing Humans. Cambridge, MA: MIT Press, 2021.