🍞 Starch, Signals & Systemic Immunity: Not All Carbs Behave Alike

🍞 Same calories—but very different immune signals.

A randomized controlled feeding trial examined 44 adults after ~15% weight loss on a very-low-carbohydrate diet. Reintroducing refined starch activated immune and metabolic pathways, increased adipsin/complement signaling, and produced activation signatures across NK cells, monocytes, T cells, dendritic cells & neutrophils. 🧬🔥

💡 Take-home: Carbohydrate quality may matter as much as quantity when considering immunometabolic effects.

⚠️ Small, selected cohort; clinical consequences remain uncertain.