
← Discovery Engines – with Nabil Laoudji23 Apr 2025 · 1 h 06 min
Unleashing Scientific Data - Nicholas Larus-Stone of Sphinx Bio, Bits in Bio
<p>Nicholas Larus-Stone is the Founder & CEO of Sphinx Bio, a startup helping life science labs unlock the full potential of their data to accelerate discovery. He’s also the Founder of Bits in Bio, a global community advancing science through software.</p><p>See below for episode links, chapters, and our socials. Hosted by Nabil Laoudji.</p><p>Support the podcast! Subscribe to our newsletter: <a href="https://www.discoveryengines.co/" target="_blank">www.discoveryengines.co</a>. Thanks for watching 🙏🤙</p><p><strong>Episode Links:</strong></p> <ul> <li><a href="https://www.linkedin.com/in/nlarusstone/" target="_blank">Nicholas' LinkedIn</a></li> <li><a href="https://www.sphinxbio.com/" target="_blank">Sphinx Bio</a></li> <li><a href="https://www.bitsinbio.org/" target="_blank">Bits in Bio</a></li> <li><a href="https://www.sphinxbio.com/post/folding-playground" target="_blank">Folding Playground</a></li> <li><a href="https://arxiv.org/abs/2502.18864" target="_blank">Google Co-Scientist Paper</a></li> <li><a href="https://www.recursion.com/" target="_blank">Recursion</a></li> <li><a href="https://medium.com/cantos-ventures/what-is-techbio-ef01cd61834d" target="_blank">Defining TechBio</a></li> </ul><p><strong>Chapters:</strong></p><ul> <li>(00:00) - Preview & Introduction</li> <li>(04:34) - Why Biotech & Life Science</li> <li>(07:33) - About Small Molecule Discovery Companies Octant & Benevolent AI</li> <li>(11:47) - Why Is Software Second in Biotech?</li> <li>(14:35) - What Engineers Bring to Biotech</li> <li>(16:00) - Is Science Data-Starved or Data Rich?</li> <li>(19:23) - How Scientists Work With Data</li> <li>(28:10) - Observations That Led to Founding Sphinx Bio</li> <li>(31:48) - AI Co-Scientists</li> <li>(37:57) - How Platforms like Sphinx Are Powered</li> <li>(40:31) - Foundation Model Companies' Interest in Science</li> <li>(43:58) - How Sphinx Leverages AI Models</li> <li>(45:59) - Managing Hallucinations</li> <li>(47:52) - Scientists: Give AI Another Try</li> <li>(49:02) - The Business and Cycles of TechBio</li> <li>(53:32) - Google's Co-Scientist, Notebook LM, and Other Science Ventures</li> <li>(57:43) - Protein Folding Playground</li> <li>(00:58:58) - "Wrapper" Companies In Era of Foundation Model Commoditization</li> <li>(01:01:56) - Bits in Bio Community & Growth</li> <li>(01:04:25) - Try Sphinx's Platform; Work for Sphinx; Support Your Local Scientist</li></ul><p><strong>Connect With Us:</strong></p><ul> <li><a href="https://www.discoveryengines.co/" target="_blank">Our Newsletter</a></li> <li><a href="https://twitter.com/nabilwrites" target="_blank">Twitter</a></li> <li><a href="https://bsky.app/profile/nabilwrites.bsky.social" target="_blank">Bluesky</a></li> <li><a href="https://www.linkedin.com/in/laoudji/" target="_blank">LinkedIn</a></li> <li><a href="https://bit.ly/7zaeqox" target="_blank">Feedback or questions</a></li></ul><p><strong>Platforms:</strong></p><ul> <li><a href="https://www.youtube.com/@discoveryengines" target="_blank">YouTube</a></li> <li><a href="https://apple.co/3DkzZrp" target="_blank">Apple Podcasts</a></li> <li><a href="https://spoti.fi/3BzMqiy" target="_blank">Spotify Podcasts</a></li></ul>