Food as Medicine: Simplifying Metabolic Health with Glyvance | Dr. Adrian Soto Mota & Brian Ruby - E457

Brian Ruby is the founder of Medifoodz, a company focused on making therapeutic ketogenic nutrition more practical, accessible, and sustainable. Through Medifoodz's Glyvance program, Ruby is combining chef-prepared ketogenic meals with continuous glucose monitoring, digital support, and clinician oversight to help patients translate metabolic health science into everyday life. His work centers on one of the biggest challenges in nutrition-based care: not simply knowing what to eat, but making it easier to consistently eat that way.

Dr. Adrian Soto-Mota, MD, PhD, FACP is an internist, metabolic researcher, and professor whose work focuses on human metabolism, ketone biology, and evidence-based approaches to metabolic disease. He earned his PhD in Physiology and Metabolism from the University of Oxford and has conducted research on exogenous ketones, glucose metabolism, and cardiovascular health.

Zetia Study: https://link.springer.com/article/10.1186/s12944-026-03034-w In this episode, Dr. Brian, Dr. Tro, Dr. Adrian, and Brian Ruby talk about…

(00:00) Intro (02:20) Why Brian Ruby founded Medifoodz (09:49) Dr. Soto Mota's recent study pitting the ADA's recommended diet and a ketogenic diet (22:28) The hardest barrier to entry most people struggle to overcome when starting a keto diet (26:15) Why CGMs are so incredibly valuable sustainability (32:16) Babies, dogs, and real food (39:24) Big Food and subsidies (45:58) Real food and dietary motivation (51:38) The AHA recommended diet diabetes reversal (59:15) Accepting and embracing criticism (01:05:51) Dr. Soto Mota's recent Zetia Study (link below) (01:18:24) Outro

For more information, please see the links below. Thank you for listening!

Links:

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Brian Ruby:

Glyvance: https://medifoodz.com/ X: https://x.com/Medifoodz

Dr. Adrian Soto Mota:

X: https://x.com/AdrianSotoMota

Dr. Brian Lenzkes: