Iron Overload & Lipid Peroxidation in Cell Death & Neurodegenerative Disease | Pamela Maher | Episode 299

Send us Fan Mail Ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation; chronoferoptosis, in which chronic stress sensitizes neurons gradually. TOPICS DISCUSSED: Cell Death Pathways: Apoptosis proceeds through regulated steps with surface “eat me” signals that enable non-inflammatory clearance by phagocytes, whereas ferroptosis and related pathways release cellular contents that can amplify local damage and inflammation.Ferroptosis Discovery: Work on glutamate toxicit...