MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302

Send us Fan Mail Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism. TOPICS DISCUSSED: Mitochondrial Roles: Not just ATP production, but “speaker of the house” via communication molecules that “talk” to the rest of the cell.Origin of Communication: Mitochondrial peptides were likely co-opted from ancient antimicrobial factors to synchronize nuclear and mitochondrial genomes.MOTC Discovery: Identified in mitochondrial ribosomal RNA regions linked to interfe...