Cutting Edge Technologies Unlocking Barrett's Esophagus Clonal Cell States

In this episode, Dr. Sydney Shaffer shares her expertise on cutting-edge technologies, including single-cell and spatial transcriptomics, and their significance for understanding cancer biology. The guest discusses these tools in the context of her recent Nature Communications publication (https://doi.org/10.1038/s41467-025-66302-w), which provides a single-cell view of cell dynamics in Barrett’s esophagus and links cell states along the disease trajectory from its origin to cancer.

#Barrett's

#Esophagus

#SpatialTranscriptomics

#Dysplasia