Dave Asprey: The Next Human Upgrade Isn’t Physical

Dave Asprey has spent more than two decades changing how millions of people think about biohacking, longevity, cognitive performance, sleep, nutrition, and human optimization. But in this conversation, the father of biohacking goes somewhere much deeper. What if the ultimate biohack isn’t physical at all?

Dave believes biohacking is evolving beyond simply optimizing the body. The next frontier may be learning to control your state, consciousness, intuition, emotional responses, and awareness—and understanding how those forces shape the way we experience reality.

In this wide-ranging conversation, Dave opens up about a side of his journey that gets far less attention: spirituality and consciousness.

Earlier in his life, Dave says he would have dismissed many spiritual practices as nonsense. His worldview was rooted in science, measurement, and evidence. But experiences with meditation, breathwork, trauma resolution, altered states, and consciousness exploration gradually forced him to reconsider what science can—and cannot yet—explain.

That journey changed his definition of biohacking.

Rather than simply changing your environment to control your biology, Dave increasingly thinks about biohacking as gaining greater control over your state. Because ultimately, most people don't really want better biomarkers. They want to feel focused, energized, calm, connected, resilient, and alive.

We also dive deeply into intuition. Can intuition actually be trained? Dave believes it can.

Using Moneyball as an analogy, Dave explains why the smartest decisions often come from combining data with intuition rather than choosing one over the other. The challenge is learning to distinguish genuine intuitive signals from fear, emotional reactivity, bias, and imagination.

Dave shares how practices including meditation, breathwork, neurofeedback, altered states, and awareness trainingmay help quiet the nervous system enough to recognize those signals.

Then we tackle one of the biggest questions in the longevity movement:

What is the point of living longer?

Dave has famously discussed dramatically extending human lifespan. But longevity, he argues, shouldn't simply mean accumulating more years. The opportunity is maintaining the energy, cognition, wisdom, relationships, purpose, and vitality necessary to make those additional years meaningful.