GLP-1s Could Be Destroying Your Muscle: Explained by Dr. Jay Campbell

Did you know you can misuse your GLP-1?

I’m with health optimization pioneer and bestselling author Dr. Jay Campbell to unpack what people are getting right and wrong about GLP-1s and peptides. We explore why these therapies can be about much more than weight loss, including their potential roles in metabolic health, muscle preservation, mitochondrial function, energy, and longevity. Most importantly, we talk about why these powerful tools still need to sit on top of the fundamentals, including protein, resistance training, healthy hormones, quality sleep, and smart metabolic habits.

What you’ll learn:

(04:19) GLP-1 therapies have evolved from early appetite-suppressing medications into newer compounds targeting multiple metabolic pathways.

(06:25) Dr. Jay Campbell believes many people use GLP-1s incorrectly and why protein, hormones, resistance training, sleep, and insulin control matter.

(07:34) Potential benefits of newer GLP-1 therapies beyond appetite suppression, including metabolic efficiency, insulin sensitivity, and changes in compulsive behaviors.

(10:38) JJ and Dr. Campbell distinguish conventional pharmaceutical dosing from the microdosing approach discussed in longevity medicine.

(16:24) Peptide purity and verification matter and what Dr. Campbell believes consumers should look for when evaluating peptide sources.

(26:06) Dr. Campbell break down the peptide and hormone categories he includes in his longevity-focused approach for adults over 45.

(29:54) Mitochondrial compounds including MOTS-c, SS-31, and NAD+ fit into the conversation around energy and healthy aging.

(34:00) Explore the emerging conversation around follistatin-related compounds and their potential role in supporting and preserving skeletal muscle.

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