NFL Week 1 Betting Preview: All 16 Games, Odds and Injuries

NFL Week 1 betting preview for the 2026 season. All 16 games, the current odds, and the full injury picture before kickoff.

We go game by game through the entire Week 1 slate, from the Wednesday night opener in Seattle on September 9 to Broncos at Chiefs on Monday night, September 14. Every game gets the market number, the availability report, and the matchup that decides it.

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