Ivermectin in Japan

Antivirals in JapanUploaded 23-11-21Ivermectin allowed as a treatment on August 13Doctors can prescribe without restrictionsPeople can buy it legally from IndiaDr. Haruo Ozaki, Chairman of the Tokyo Medical Associationhttps://www.tokyo-np.co.jp/article/123988The situation is that the whole country is suffering from disasters. No one will listen to me, so I will come up with a new policyThe antiparasitic drug "ivermectin" shows the number of infections and deaths of the new corona in a country that is prophylactically administered for another disease in Africa.It is necessary to thoroughly study the clinical trial, but it seems that we are at the stage where it is okay to have the patient give an informed outlet and get permission to use itJapanhttps://www.japantimes.co.jp/news/2021/11/22/national/japan-coronavirus-november22/Population, 126 millionCases, + 79Deaths, + 2Lowest since June 23, 2020Currently reopeningMore than 76% of population is fully vaccinated(South Korea, high vaccination but uptick in infections)Boosters to start in DecemberIngrained pre-pandemic flu seasons mask wearingDelta variant wave endsDelta variant “self-extinction”Viral genetic mutationsIturo Inoue, professor, National Institute of GeneticsDelta variant in Japan accumulated too many mutationsVirus’s error-correcting protein, nsp14Majority of nsp14 specimens in Japan seemed to have undergone many genetic changes in mutation sites called A394VNon-structural protein, made by the virusTherefore errors accumulated leading to non-viabilityAlsoMore people in Asia have a defense enzyme called APOBEC3A that attacks RNA viruses, Including the SARS-CoV-2 virus that causes COVID-19, when compared to people in Europe and Africa.National Institute of Genetics and Niigata UniversityResearch to discover how the APOBEC3A protein affects the nsp14 proteinA394V discovered in 24 other countriesSARS ended abruptly in 2003Working on a drug to inhibit nsp14 Learn more about your ad choices. Visit megaphone.fm/adchoices

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