120: From PCOS to PMOS; Why Hormones Are Not the Only Problem

In this interview with Terri DeNeui, we explore why the conversation around PCOS is shifting toward a broader understanding of metabolic health with the emerging term PMOS.

Rather than viewing irregular cycles, infertility, and hormone imbalances as isolated ovarian problems, we discuss how insulin resistance, gut health, inflammation, stress, and lifestyle factors may be driving many of the symptoms women experience. I also share why this updated perspective could change the way clinicians evaluate and support patients across different stages of life—not just during their reproductive years.

We also spend time talking about practical treatment considerations, from comprehensive lab testing and lifestyle interventions to the appropriate role of GLP-1 medications.

Topics We Cover in This Episode: 

Why some experts are moving from the term PCOS to PMOS—and what that shift represents

How insulin resistance and gut health may influence hormone balance

Why irregular menstrual cycles deserve a broader metabolic evaluation

The role inflammation and stress may play in hormone-related symptoms

Why body composition can be a more meaningful measure than weight alone

How to think about GLP-1 medications as one tool rather than a complete solution

Practical lifestyle habits that support long-term metabolic and hormonal health

Why treating symptoms without addressing underlying metabolic dysfunction may leave important questions unanswered