ACL Prevention with Digital Twin (AI) to Aid in Knee Assessment and Risk Analysis for the ACL Tear

In this episode of HSS Presents, radiologist Dr. Harry G. Greditzer IV speaks with Dr. Andrew D. Pearle, Chief Emeritus of the Sports Medicine Institute at HSS, about the evolution of computer-assisted surgery and the emerging role of digital twins in orthopedics. Dr. Pearle explains how patient-specific MRI models, computational biomechanics, and additional data inputs may help clinicians assess ACL-injury risk, simulate surgical approaches, and personalize treatment planning. The conversation highlights neuromuscular training—a combination of strength, agility, plyometric, and landing-stabilization exercises—as an important strategy for reducing injuries among young athletes. Looking ahead, they also discuss how digital twins could support more individualized prevention, informed decision-making, and treatments designed around each patient’s anatomy, movement patterns, and activity goals.