
← Sugar & Strength Podcast19 feb · 1 h 01 min
What to Know About Ozempic & GLP-1 Medications: Weighing the Nutritional Risks, Rewards & Trade-Offs
<p>In this episode, Kayla Girgen, RD, CPT, offers a balanced, honest breakdown of the nutritional risks, metabolic trade-offs, and real-world benefits of GLP-1 receptor agonist medications.</p><p></p><p>These drugs are powerful tools, but they also come with side effects, financial commitment, and lesser-discussed concerns—like changes in motivation, mood, and enjoyment of food. You’ll learn:</p><ul><li>How GLP-1 receptor agonists work</li><li>The difference between semaglutide and tirzepatide</li><li>The most common and overlooked side effects</li><li>Why muscle loss is one of the biggest risks—and how to prevent it</li><li>What “anhedonia” is and why it matters</li><li>What happens when you stop taking a GLP-1 medication</li><li>The financial and physiological realities of long-term use</li><li>The critical role of strength training and nutrition while on these drugs<p></p></li></ul><p>If you’re currently taking a GLP-1 medication, considering one, or simply curious about the hype, this episode will help you think critically and protect your future health.</p><p><br /></p><p><b>Chapters:</b></p><p>00:00 Introduction to the Complexities and Considerations of GLP-1 Medications<br />09:33 Active Ingredients, Brand Names & Terminology for GLP-1 Medications<br />13:52 Incretin Effect of GLP-1 and GIP<br />18:01 GLP-1 Injectables, Pills, and Compounding Pharmacies<br />20:20 Cardiometabolic Benefits of GLP-1 Agonist Medications<br />24:08 Warning About Oral Birth Control and GLP-1 Cessation Before Medical Procedures<br />29:09 Benefits of GLP-1 Agonist Medications<br />32:23 Side Effects of Semaglutide and Tirzepatide<br />38:08 Muscle Loss and How To Minimize It<br />46:49 "Anhedonia": A Less-Known Side Effect of GLP-1RAs<br />51:46 Sustainability, Cost, and Weight Regain<br />55:49 Closing Thoughts and Considerations<br /><br /></p><p><b>Keywords:</b><br />Side effects of GLP-1 weight loss medications, Mounjaro vs Ozempic, GLP-1 receptor agonists explained, semaglutide vs tirzipatide, muscle loss on GLP-1 medications, long-term effects of GLP-1 meds, how to prevent weight regain after Ozempic</p><p><br /><br /><b>🔗Links Mentioned In This Episode:<br /></b><br /><a rel="noopener noreferrer nofollow" href="https://kaylagirgenrd.com/semaglutide-diet-plan/" target="_blank">Blog Post: GLP-1 Diet Plan: How to Lose Weight Without Losing Muscle</a></p><p><a rel="noopener noreferrer nofollow" href="https://curehydration.pxf.io/OeXQkz" target="_blank">Shop Cure Electrolytes<br /></a>*Use KAYLA for 20% off</p><p><a rel="noopener noreferrer nofollow" href="https://kaylagirgenrd.mn.co/plans/1951992?bundle_token=83e58dd57f0d50c80b082b21b87a7a40&utm_source=manual" target="_blank">Join the Sugar & Strength Academy<br /></a>*Try for FREE! Your first week is on me.</p><p><a rel="noopener noreferrer nofollow" href="https://forms.gle/KX5ryZeHmc8Lyjup8" target="_blank">Apply to Work with Kayla</a></p><p><a rel="noopener noreferrer nofollow" href="https://tr.ee/ogZH-M81C1" target="_blank">Submit Your AMA Question(s)</a></p><p></p><p><b>More from Kayla:</b></p><p><a rel="noopener noreferrer nofollow" href="https://amzn.to/467FDZR" target="_blank">Ruck Fit: Build Strength and Endurance by Walking with Weight</a></p><p><a rel="noopener noreferrer nofollow" href="https://grocerylist.gr8.com/" target="_blank">Free Dietitian-Approved Food List</a></p><p><a rel="noopener noreferrer nofollow" href="https://cgmguide.gr8.com/" target="_blank">Download Kayla’s Free CGM Guide</a></p><p><a rel="noopener noreferrer nofollow" href="https://www.instagram.com/kaylagirgenrd/" target="_blank">Follow on Instagram</a></p><p><a rel="noopener noreferrer nofollow" href="https://www.youtube.com/@kaylagirgenrd" target="_blank">Subscribe on YouTube</a></p><p><a rel="noopener noreferrer nofollow" href="https://kaylagirgenrd.com/" target="_blank">Kayla's Website</a></p>