Dr. John Campbell

← Dr. John CampbellNouveau · 28 min

Delta, double hospital risk

Delta, double hospital riskNouveau28 min

NZ, Australia and Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort studyhttps://www.health.govt.nz/our-work/diseases-and-conditions/covid-19-novel-coronavirus/covid-19-data-and-statistics/covid-19-current-casesUploaded 28-08-21https://www.health.gov.au/news/health-alerts/novel-coronavirus-2019-ncov-health-alert/coronavirus-covid-19-case-numbers-and-statisticsHospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort studyhttps://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00475-8/fulltexthttps://www.bbc.co.uk/news/health-58354342Public Health England (PHE) and Medical Research CouncilSARS-CoV-2 delta (B.1.617.2) first detected in England in March, 2021Suspected to cause more severe disease than alpha (B.1.1.7)Determining the relative risk of hospital attendanceEngland between March 29 and May 23, 2021All infected with alpha or deltaPublic Health England’s Second-Generation Surveillance SystemCOVID-19-associated deaths datasetNational Immunisation Management SystemNHS Digital Secondary Uses Services and Emergency Care Data SetInfectionsn = 43,338 COVID-19-positive patientsMost patients were unvaccinated, 32,078 (74·0)Median age 31, (IQR, 17 – 42)Delta = 8,682Alpha = 34,656Admitted to hospital or sought emergency care within 14 days of positive testDelta = 498 (5.7%)Alpha = 1,448 (4·2%)Adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination statusHR for attendance at emergency care or hospitalisation = 1.45HR for hospital admission = 2.26In the subgroup of vaccinated patientsNo significant difference between variants for emergency visit or hospitalisationInterpretationThis large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant. Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant.PHE studies and protection against hospital admissionhttps://khub.net/web/phe-national/public-library/-/document_library/v2WsRK3ZlEig/view/47960726696% for the Pfizer-BioNTech vaccin92% for the Oxford-AstraZeneca vaccineUK rates47.9 million people, (88%) aged 16 and over, first dose of a