EXPLAINER: How To Live To 117

She lived to 117 — and when scientists sequenced everything from her genome to her gut bacteria, they found a paradox that rewrites what aging has to look like. In this episode, Robert Lufkin MD breaks down the landmark multiomics study of Maria Branyas Morera, the world's oldest verified person, published in Cell Reports Medicine (2025) by the Esteller lab. The study mapped her genome, epigenome, proteome, metabolome, and microbiome — and found a body that was simultaneously very old and bio...