202 Prescription-Grade THC-Free CBD for Pain, Anxiety, and Sleep: Pulak Sharma on Cope Now

202 Prescription-Grade THC-Free CBD for Pain, Anxiety, and Sleep: Pulak Sharma on Cope Now

Host Marie Betcher, RN and former hospice nurse, interviews Pulak Sharma, founder of Kazmira and creator of Cope Now, a vertically integrated telemedicine, compounding pharmacy, and manufacturing platform providing prescription, pharmaceutical-grade THC-free CBD. Sharma explains their CGMP-validated hemp extraction and purification process, compounding into an oral tincture in three strengths, delivery to patients, and development of a shelf-stable nano-emulsion. He says patients most commonly seek help for anxiety and pain, and notes many consumer CBD products are underdosed, citing therapeutic ranges of roughly 200–400 mg/day and typical prescribing around 300 mg/day, with protocols for titration and liver enzyme concerns. They discuss CBD's non-scheduled status, lower side-effect profile compared with opioids/benzodiazepines, clinician and pharmacist oversight for dosing and interactions, and batch testing showing non-detect THC to avoid psychoactive effects and THC-positive urine tests.

00:00 Welcome and Disclaimer

00:29 Meet the Guest and Episode Focus

02:07 How Cope Now Works

03:06 Product Formats and Strengths

03:53 Top Uses and Proper Dosing

05:25 Hospice Needs and Opioid Alternatives

08:52 Titration and Daily Timing

12:04 Telemedicine Intake and Prescribing

13:32 Founder Story and Older Patients

16:14 Closing the Guidance Gap