Can GLP-1s Lower Your Sex Drive? Sexual Medicine Expert Jackie Giannelli Explains

<p>Why are women's health issues often brushed off as “just part of aging”?</p><p>In this eye-opening episode, Natassia sits down with board-certified family nurse practitioner, women's longevity and sexual medicine expert <a href="https://jackiegiannellinp.com/" rel="ugc noopener noreferrer" target="_blank">Jackie Giannelli</a> to unpack the truth about perimenopause, menopause, libido, hormone replacement therapy, GLP-1 medications, hair loss, testosterone, vaginal estrogen, peptides, and sexual wellness. They explore why so many women feel dismissed when experiencing brain fog, fatigue, low desire, anxiety, and disrupted sleep and what can actually be done about it. </p><p>From the controversy surrounding hormone therapy and breast cancer fears to the surprising effects of GLP-1 medications on libido and pleasure, this conversation challenges outdated medical narratives and offers practical insights for women who want to reclaim their vitality, confidence, relationships, and long-term health. If you've ever wondered whether feeling “flat” is normal, this episode may change the way you think about aging and wellness.</p><p><br /></p><p>00:00 – Welcome and introduction</p><p>01:15 – Why women feel dismissed by healthcare</p><p>02:58 – The first signs of perimenopause</p><p>05:25 – Sleep, libido, brain fog, and hormone decline</p><p>06:25 – Normal vs. optimal hormone levels</p><p>09:41 – Medical gaslighting and menopause care</p><p>11:32 – When hormones aren't the whole story</p><p>13:05 – Testosterone therapy for women</p><p>15:03 – Understanding estrogen, progesterone, and hormone balance</p><p>17:28 – Bioidentical vs. synthetic hormones</p><p>19:19 – The Women's Health Initiative controversy</p><p>22:04 – Breast cancer fears and hormone therapy</p><p>24:52 – Feeling flat, dopamine, and SSRIs</p><p>26:10 – GLP-1 medications and sexual side effects</p><p>29:20 – Combining hormones with GLP-1 treatment</p><p>32:08 – Long-term concerns about GLP-1 medications</p><p>36:12 – Hair loss, hormones, and weight loss drugs</p><p>41:37 – Peptides explained</p><p>44:01 – The peptide regulation gray area</p><p>46:00 – PT-141, Addyi, and female libido treatments</p><p>51:16 – Why vaginal estrogen is underused</p><p>54:13 – Designing a home for intimacy and connection</p><p>57:08 – The science of music and arousal</p><p>59:00 – Closing thoughts</p><p><br /></p><p><a href="https://www.instagram.com/jackie.giannellinptalks/" rel="ugc noopener noreferrer" target="_blank">F