Thrombosis & Bleeding in CLL: Risk, Mechanisms, and Practical Management in the Targeted-Therapy Era

Drs. Scarfò and Ghia discuss how CLL creates a delicate balance between blood clots and bleeding, a challenge made more complex by BTK inhibitors and common comorbidities in older patients. They explore how careful risk assessment, thoughtful use of anticoagulants, and close patient communication are essential to keep treatment both effective and safe.