The Gene Variant Linked to Living to 100 | Pinchas Cohen | 304

Send us Fan Mail Mitochondrial peptides act as stress signals that regulate metabolism, muscle mass, and neurodegeneration. TOPICS DISCUSSED: Mitochondria as Communication Hubs: Beyond ATP production, mitochondria encode peptides that regulate cell death, immunity, and inter-organ communication.Humanin Discovery: Identified independently by three labs; neuroprotective, longevity-linked, and capable of neutralizing APOE4 effects via a rare Jewish variant.Ethnic Genetic Variants: Ancestry-speci...