What we're getting WRONG about the "leaky" aging brain | William Banks | 300

Send us Fan Mail Blood-brain barrier as a dynamic interface allowing selective passage of nutrients, peptides, and gut hormones. TOPICS DISCUSSED: Blood-Brain Barrier Structure: Capillary endothelial cells with tight junctions, absent fenestrae, and minimal vesicles create a selective interface; supported by astrocytes and pericytes.Crossing Mechanisms: Lipid-soluble small molecules diffuse passively; glucose, amino acids, and regulatory peptides use saturable transporters whose rates vary by...