The New Frontier of Dementia Prevention with Cédric Gousseau

<p>In this episode of the Brain Health Kitchen podcast, Annie talks with Cédric Gousseau, co-founder of BetterBrain, about what it means to be proactive about brain health before symptoms begin.</p><p>Cédric came to this work personally after learning in his early twenties that he carries an APOE4 gene variant, which increases risk for late-onset Alzheimer’s disease. That discovery led him deep into the science of dementia prevention and the question so many people ask: if I care about my brain health, where do I start?</p><p>Annie and Cédric talk about the promise and complexity of genetic testing, why APOE4 is a risk factor but not a diagnosis, and how people may use that information to make more targeted choices. They also discuss brain health biomarkers that are not always included in a routine doctor’s visit, including homocysteine, APOB, Lp(a), B vitamins, inflammation markers, and newer tests like p-tau 217.</p><p>The bigger theme is what happens after testing. Cédric explains why numbers alone are not enough, and why interpretation, coaching, and follow-through matter if people are going to turn brain health information into real-life changes.</p><p>This episode is for anyone who wants to move from worry to a plan — and understand what proactive brain care may look like in the years ahead.</p><p>Chapters</p><p>07:07 — Discovering APOE4 in his early 20s</p><p>10:56 — The emotional impact of genetic risk</p><p>12:10 — Should you know your APOE4 status?</p><p>17:33 — From personal risk to building Better Brain</p><p>22:29 — How a personalized brain health system works</p><p>25:03 — Why testing alone is not enough</p><p>38:27 — APOE4 and p-tau217 testing</p><p>44:52 — Brain health labs beyond a standard panel</p><p>46:15 — Homocysteine and B vitamins</p><p>49:11 — ApoB, Lp(a), and vascular risk</p><p>52:42 — Can brain health become the next preventive cardiology?</p><p>56:08 — Preventive cognitive testing</p><p>1:00:30 — Personalized AI and brain health</p><p>1:04:09 — The future of dementia prevention </p><p><br /></p><p><b>Links</b></p><p><b>About Better Brain and Cédric Gousseau<br /></b><a rel="noopener noreferrer nofollow" href="https://www.betterbrain.com/about-us?utm_source=chatgpt.com" target="_blank"> </a><a rel="noopener noreferrer nofollow" href="http://betterbrain.com/about-us" target="_blank">betterbrain.com/about-us</a></p><p></p><p><b>Brain Health Kitchen<br /></b><a rel="noopener noreferrer nofollow" href="https://brainhealthkitchen.sub