#477: Stimulate Don't Suppress: How Natural GLP-1 Hormones Beat Synthetic for Sustainable Fat Loss | Clinical Results With Sarah Kennedy

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Today, I’m joined by Sarah Kennedy of CaloCurb, a remarkable veterinarian-turned-nutrition expert who brings decades of hands-on research and real-world insight to the weight loss conversation. Sarah shares her unique journey from studying animal nutrition—where performance and health are paramount—to spearheading groundbreaking human clinical trials in appetite regulation, hunger hormones, and innovative, natural GLP-1 strategies.

Learn more about Calocurb at https://www.calocurb.com/?sca_ref=12093749.1gzbGYmTyb and use code NAT for 10% off.

Episode Timestamps:

Welcome and gratitude for listeners ... 00:00:00

Calocurb and GLP-1 context ... 00:02:07

Bitter taste receptors and appetite suppression ... 00:17:13

Discovery of hops as key bitter extract ... 00:20:13

Human trials: hormone changes and calorie reduction ... 00:21:00Comparison to pharmaceutical GLP-1s ... 00:21:44

Appetite studies: women vs. men ... 00:25:15

Recent clinical trial: fat loss, muscle preservation ... 00:28:37

Mechanisms: natural vs. synthetic hormone activation ... 00:31:38