GLP-1's Explained with Ashley Koff, RD

GLP-1s seem to be everywhere right now, from social media to popular television commercials to your neighbors down the street. Yet most of us don’t understand what they are or how they work. In this episode of Meet Your Body, Jessica sits down with registered dietitian Ashley Koff, RD, to cut through the hype, fear, and misinformation surrounding GLP-1 medications. Ashley breaks down the science of GLP-1s, GIP, peptides, and weight-health hormones in a way that finally makes sense—and explains what you should know before making decisions about medication, nutrition, or your next step.

You'll learn:

What GLP-1, GIP, and peptide hormones actually are

Who may be a candidate for GLP-1 medication—and who may not be

The questions to ask your healthcare provider before starting a GLP-1

What symptoms and side effects to be aware of

How GLP-1’s may be a tool for some women but must be partnered with habits such as exercise, proper nutrition, nervous system nourishment and more

Ashley and Jessica also discuss a bigger issue: weight is not the same thing as health. They explore how weight stigma and shame can interfere with care, why individual context matters, and how nourishment, movement, sleep, nervous system support, and body connection remain important regardless of whether medication is part of your plan.

If you've heard about Ozempic, Wegovy, Mounjaro, Zepbound, or GLP-1s and feel confused, skeptical, curious—or simply want reliable information before forming an opinion—this conversation is for you.

About our guest:

Ashley Koff, RD, is the USA Today bestselling author of Your Best Shot (HarperOne) and founder of The Better Nutrition Program (BNP).

With over twenty-five years of experience, Ashley’s helped redefine how we approach sustainable, lasting weight health. In her new book, Your Best Shot, Ashley introduces weight-health hormones (GLP-1, GIP, CCK, PYY)  and offers the first-ever system for assessing and optimizing these hormones, whether you're using GLP-1 medication or not.