412: Depression; through the lens of the teenage brain. An 'Inside the Teen Brain' podcast

Dr. Jane Gilmour returns with Inside the Teen Brain. In this episode Jane talks to Dr. Victoria Pile about depression.

This talk explores the presentation, recognition, and psychological intervention for depression in adolescence, a developmental period marked by heightened vulnerability and significant opportunity for intervention. Depression commonly emerges during adolescence and is associated with substantial long-term consequences, including social and academic impairment.

Despite its prevalence and impact, the majority of young people with depression do not receive timely or effective support. The talk highlights how adolescent depression is often under-recognised, perhaps due to its overlap with developmental changes and its heterogeneous clinical presentation.

Recent work that highlights central symptoms of depression is discussed. Current treatment approaches are described and evidence explored that suggests many established interventions show only modest efficacy, and a substantial proportion of young people do not respond. In response, emerging approaches are discussed that aim to improve both access and effectiveness. These include school-based delivery models and the co-development of treatments with young people.

Finally, the talk considers a shift toward targeting specific symptoms and psychological mechanisms, such as self-compassion, sleep, and emotional mental imagery. Novel interventions are presented as promising avenues for improving outcomes. Overall, the talk suggests a more developmentally informed, accessible, and mechanism-focused approach to addressing adolescent depression.

Learning Objectives

To understand the presentation and challenges of recognising adolescent depression.

To appreciate the effectiveness and limitations of current psychological interventions for adolescent depression

To explore emerging, developmentally informed approaches to intervention

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