182. Osteoarthritis Isn’t Just “Wear & Tear”… So What Is It, Really?

Send us Fan Mail OA is described as the most prevalent chronic joint disease worldwide, involving progressive degeneration of articular cartilage and sometimes subchondral bone, leading to pain, stiffness, and functional limitations. Rather than simple “wear and tear,” OA is a multifactorial whole-joint condition influenced by inflammatory, mechanical, and metabolic factors, with risk increased by age, obesity, mechanical stress, and joint trauma. The episode reviews how this happens, what ph...