TWiV 1361: Ancient Viral Sword and Shield

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer's Disease neuropathology evolved as a host defense response to microbial infection in the brain.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode Support science education at MicrobeTV Bob Tesh dies (Galv News) Comment on propsed changes to NIH peer review (NIH) NIH peer review proposed changes (Forbes) Ancient RNA guided DNA recognition (Science) Noncontiguous geometric triplex (Science) p-tau has anti-herpes virus activity (Nat Neurosci) Letters read on TWiV 1361 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – APoD September 14: Origins of Elements

Alan – Redshirts, by John Scalzi

Vincent – Prone to Bruise by David Molesky he's at Spring/Break till 9/28

Listener Pick Anne – Nikon Small World in Motion Competition

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.