Episode 208 — GLP-1s, Muscle Loss & Longevity: What Men Over 40 Need to Know | Dr. Q

Are GLP-1 medications just another weight-loss trend — or are they changing the way we think about obesity and metabolic health?

And if you're using one, are you putting your muscle at risk?

In this episode of the Over 40 Alpha Podcast, I sit down with board-certified internal medicine physician Dr. Furhan Qureshi — Dr. Q — for a wide-ranging conversation about GLP-1s, metabolic health, testosterone, muscle, modern medicine, longevity and why so many men feel like they're fighting an uphill battle after 40.

Dr. Q works on both ends of medicine: treating critically ill patients in the hospital while also focusing on prevention and optimization in his wellness practice. Early in our conversation, he explains why he believes medicine has become very good at treating disease but still has major gaps when it comes to preventing it.

And that's where this conversation gets interesting.

We talk about why our modern lifestyle has made movement optional, why sitting, driving and screen time matter, why more men are looking for quick fixes for low energy and low testosterone, and why medication should never replace addressing the underlying problem.

Then we go deep into GLP-1 medications.

Dr. Q explains how they work, why his own opinion of them changed, the benefits he believes the evidence is beginning to reveal, and the potential risks and side effects that shouldn't be ignored.

We also tackle one of the biggest questions for men over 40:

Do GLP-1s cause muscle loss?

Dr. Q explains that GLP-1s don't simply "attack" muscle; rather, inadequate food and protein intake combined with a lack of resistance training may contribute to loss of lean mass during significant weight loss.

That's especially important after 40 because muscle isn't just about looking good.