Accelerating Cancer Research - Hani Goodarzi of Arc Institute, UCSF, Exai Bio

<p>Hani Goodarzi is Quantitative and Computational Biologist, Core Investigator at the Arc Institute, Associate Professor at UCSF, and co-founder of Exai Bio and Vevo Therapeutics. Episode links and chapters below.</p><p>Hosted by Nabil Laoudji. Support the podcast! <a href="https://www.discoveryengines.co/" target="_blank" rel="ugc noopener noreferrer">Subscribe to our newsletter</a>. Thanks for watching 🙏🤙</p><p><strong>Episode Links:</strong></p><ul><li><a href="https://arcinstitute.org/" target="_blank" rel="ugc noopener noreferrer">Arc Institute</a></li><li><a href="https://arcinstitute.org/labs/goodarzilab" target="_blank" rel="ugc noopener noreferrer">Goodarzi Lab</a></li><li><a href="https://www.exai.bio/" target="_blank" rel="ugc noopener noreferrer">Exai Bio</a></li><li><a href="https://www.vevo.ai/" target="_blank" rel="ugc noopener noreferrer">Vevo Therapeutics</a></li><li><a href="https://cancer.ucsf.edu/people/goodarzi.hani" target="_blank" rel="ugc noopener noreferrer">UCSF Cancer Center</a></li><li><a href="https://www.linkedin.com/in/hgoodarzi/" target="_blank" rel="ugc noopener noreferrer">Hani's LinkedIn</a></li><li><a href="https://x.com/gdb/status/1864052838256808339?lang=en" target="_blank" rel="ugc noopener noreferrer">Greg Brockman's Post</a></li><li><a href="https://www.cancer.gov/about-cancer/understanding/statistics" target="_blank" rel="ugc noopener noreferrer">NCI Cancer Stats</a></li></ul><p><strong>Chapters:</strong></p><ul> <li>(00:00) - Teaser</li> <li>(02:12) - Episode Introduction &amp; Preview</li> <li>(07:35) - Hani’s Path Into Quantitative and Computational Biology</li> <li>(11:55) - The Emerging Promise of Foundation Models Such as Evo 2</li> <li>(15:53) - Dry Side vs. Wet Side of Biology</li> <li>(22:23) - Pivoting Into AI for Life Science From Unrelated Domains, and the Importance of Culture in Cross-Functional Teams</li> <li>(27:28) - How to Develop Multidisciplinary Teams: Brutal Honesty</li> <li>(30:07) - How Arc Institute’s Org and Funding Structure Enables Innovative Science</li> <li>(36:24) - How Tech Founders Are Pushing Biotech Innovation</li> <li>(39:07) - Hani’s Collaboration with NVIDIA and Greg Brockman of OpenAI</li> <li>(43:57) - The Science Behind Exai’s Early Cancer Detection Platform</li> <li>(52:05) - DNA Methylation to Improve Cancer-Specific Signals From Blood</li> <li>(55:25) - UCSF’s Application of This Technology for Breast Cancer Detection</li> <li>(58:34) - How Startups Help Bridge the Science “Valley of Death”</li> <li>(01:04:24) - Supporting Hani’s Work Through Scientific Contributions, Evangelism, and Applying the Scientific Method Across Disciplines</li></ul><p><strong>Connect With Us:</strong></p><ul> <li><a href="https://twitter.com/nabilwrites" target="_blank" rel="ugc noopener noreferrer">Twitter</a></li> <li><a href="https://bsky.app/profile/nabilwrites.bsky.social" target="_blank" rel="ugc noopener noreferrer">Bluesky</a></li> <li><a href="https://www.linkedin.com/in/laoudji/" target="_blank" rel="ugc noopener noreferrer">LinkedIn</a></li> <li><a href="https://www.instagram.com/nabilwrites" target="_blank" rel="ugc noopener noreferrer">Instagram</a></li> <li><a href="https://www.discoveryengines.co/" target="_blank" rel="ugc noopener noreferrer">Newsletter</a></li> <li><a href="https://bit.ly/7zaeqox" target="_blank" rel="ugc noopener noreferrer">Feedback or questions</a></li></ul><p><strong>Platforms:</strong></p><ul> <li><a href="https://www.youtube.com/@discoveryengines" target="_blank" rel="ugc noopener noreferrer">YouTube</a></li> <li><a href="https://apple.co/3DkzZrp" target="_blank" rel="ugc noopener noreferrer">Apple Podcasts</a></li> <li><a href="https://spoti.fi/3BzMqiy" target="_blank" rel="ugc noopener noreferrer">Spotify Podcasts</a></li></ul>