Lab leaks

Accidentally on purposeUploaded 18-01-24https://dictionary.cambridge.org/dictionary/english/accidentally-on-purposeWEF prepares for Disease Xhttps://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/preparing-for-a-disease-x/?utm_source=substack&utm_medium=emailLaboratory-acquired infections and pathogen escapes worldwide between 2000 and 2021https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00319-1/fulltextLaboratory-acquired infections (LAIs),and accidental pathogen escape from laboratory settings (APELS),are major concerns for the community. A risk-based approach for pathogen research management,within a standard biosafety management framework is recommended,but is challenging.due to reasons such as inconsistency,in risk tolerance and perception.Here, we performed a scoping review,using publicly available, peer-reviewed journal and media reports,of LAIs and instances of APELS between 2000 and 2021.Laboratory-acquired infections (LAIs)309 individuals, 94 reports for 51 pathogens. Eight fatalities2·6% of all LAIsNeisseria meningitidis (n=3, 37·5%)Yersinia pestis (n=2, 25%)Salmonella enterica serotype Typhimurium (n=1, 12·5%)Ebola virus (n=1, 12·5%)Bovine spongiform encephalopathy (n=1, 12·5%)Accidental pathogen escape from laboratory settings (APELS)16 APELS were reportedBacillus anthracis (anthrax)SARS-CoVPoliovirusBrucella spp (brucellosis zoonosis) Foot and mouth disease virusInfluenza virus H5N1Examplesthe discovery of historical variola virus ampoules in cold storage during a move of laboratories at the National Institutes of Health campus in Bethesda, MD, USA in July, 2014the shipment of live anthrax cultures from US Department of Defense laboratories following incomplete inactivationLethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2- related Pangolin Coronavirus GX_P2V(short_3UTR) https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full.pdfSARS-CoV-2-related pangolin coronavirus GX_P2V can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. This underscores a spillover risk of GX_P2V into humanshttps://www.biblegateway.comThen another horse came out, a fiery red one. Its rider was given power to take peace from the earth and to make people kill each other. To him was given a large sword. (Revelation chapter 6, v 4) Learn more about your ad choices. Visit megaphone.fm/adchoices

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