#155 - Meet The World’s Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of

<p>🧠 JOIN THE GIANT&#39;S SHOULDER FAMILY</p><p>Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 </p><p>https://www.youtube.com/@thegiantsshoulder/join</p><p><br></p><p>Steven Barker is the chemist who has spent fifty years proving your brain makes its own psychedelic. He built the mass-spectrometry methods sensitive enough to find DMT in living tissue, and showed it sits in the brain at concentrations rivalling serotonin and dopamine. In 1981 the war on drugs cut his funding and the work stopped for fifteen years. He also synthesised his own supply — and took it.</p><p><br></p><p>Expect to learn:</p><p>- The locked cabinet: what his mentor kept behind two locks, and why Barker raided it</p><p>- The missing neurotransmitter: why DMT meets every formal criterion and nobody noticed</p><p>- Machine elves: why he calls the term marketing rather than science</p><p>- DMT immunity: the lab technician who took a full dose and felt nothing</p><p>- Receptors inside the neuron: the 2023 finding that explains the neuroplasticity</p><p><br></p><p>SPONSORS</p><p>Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiants</p><p><br></p><p>GS EPISODES MENTIONED</p><p>Andrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDA</p><p>Rick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYsc</p><p>Dennis McKenna - Dennis McKenna: &quot;I&#39;ve Spent 50 Years Investigating The Entities That Exist Within Ayahuasca&quot;: https://youtu.be/gTSBhfZhuD8</p><p>David Nichols - Meet The Greatest Living Psychedelic Scientist You&#39;ve Never Heard Of: https://youtu.be/6umTgXsW1lQ</p><p><br></p><p>GUEST LINKS</p><p>ResearchGate Profile: https://www.researchgate.net/scientific-contributions/Steven-A-Barker-2164230436</p><p>N,N-Dimethyltryptamine, an Endogenous Hallucinogen (2018 review): https://doi.org/10.3389/fnins.2018.00536</p><p>A Critical Review of Endogenous DMT in Humans 1955-2010 (with Strassman): https://doi.org/10.1002/dta.422</p><p>LC/MS/MS Analysis of Rat Pineal Microdialysate (2013, the paper discussed on tape): https://doi.org/10.1002/bmc.2981</p><p>Administration of DMT in Psychedelic Therapeutics (2022 review): https://doi.org/10.1007/s00213-022-06065-0</p><p><br></p><p>LISTEN ON</p><p>Spotify - https://open.spotify.com/show/5m3Gta5MtIYd